We specialize in next generation sequencing (NGS) technologies and genomics data science. We work closely with researchers from study design and conceptualisation to advanced data analysis.
We regularly contribute to large-scale interdisciplinary research projects and develop data processing pipelines and tools for data exploration and visualisation. We are equipped with state-of-the-art computational infrastructure and have access to a comprehensive software repository.
We train the next generation of bioinformaticians through our own research projects, specific courses and our Master program in Bioinformatics and Computational Biology.
Icons: Icongeek26, Smashicons, Eucalyp and Freepik from Flaticon.
The detailed program will be available in early-March.
OpenGenomeBrowser: a versatile, dataset-independent and scalable web platform for genome data management and comparative genomics
Together with the Next Generation Sequencing Platform (NGSP) we are looking for a bioinformatician to build and maintain bioinformatics expertise at the NGSP. Details can be found here.
IBU will be at Nacht der Forschung 2022. Come visit us at room 117 in the main building (Hochschulstrasse 4), we will be there between 4pm and midnight.
LEGO und Erdeeren? Erbgut erforschen.
At the SIB Bioinformatics Summit conference, Thomas Roder received an award for the software "OpenGenomeBrowser" poster presentation.
You can check out his website here.
Together with Philippe Plattet of Neurovirology at Vetsuisse and the Group of Markus Seeger at UZH we have published a paper on how synthetic nanobodies can help to cure COVID now and in the future.
The project “Machine learning models in the prediction of kidney stone recurrence”
was awarded to Prof. Dr. Daniel Fuster and PD Dr. Rémy Bruggmann for full funding in the CAIM Research Funding Call 2021/22.
Biogenic amines in cheese may pose a risk to consumers. Researchers from the University of Bern and Agroscope provide a detailed insight about the biogenic amine producing bacterium Morganella morganii.
OpenGenomeBrowser is a self-hostable, open-source software that manages access to genomic databases and drastically simplifies basic comparative genomics analysis steps. It allows users to filter genomes based on metadata, create phylogenetic trees, search for annotations, align genes, compare gene loci, interactively browse biochemical pathways, study dotplots, search for orthologous genes, perform gene trait matching, execute BLAST searches, and access the raw data.
We have set up new analysis workflows for spatial transcriptomics and epigenomics.
Check out our services page for more information.
The BBBHub is a data hub which centralizes and organizes raw and processed RNA-Seq data from reserch in the field of Brain Barriers. This data hub is spearheaded at the Interfaculty Bioinformatics Unit of the University of Bern and is part of the European network BtRAIN.
It is already known that zebrafish can flexibly regenerate their hearts after injury. An international research group led by Prof. Nadia Mercader of the University of Bern now shows that certain heart muscle cells play a central role in this process. The insights gained could be used to initiate a similar repair process in the human heart.
Collegium Generale Lecture Series: Dr. Rémy Bruggmann, head of the IBU and BCPM management board member, speaks about Bioinformatics und new Sequencing Technologies (Podcast in German).
The latest publication of Dr. Rémy Bruggmann can be found on elifesciences.org.
The Interfaculty Research Cooperation "One Health: Cascading and Microbiome-Dependent Effects on Multitrophic Health" examines causal relationships between environmental, animal and human health. We investigate how environmental chemicals such as heavy metals, pesticides and plant secondary metabolites affect microbial communities and health at the interfaces between soils, plants, animals and humans. By unraveling underlying mechanisms, our work contributes to a better understanding of integrated health and supports the development of healthy food chains.
[Text from onehealth.unibe.ch]
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