We specialize in next generation sequencing (NGS) technologies and genomics data science. We work closely with researchers from study design and conceptualisation to advanced data analysis.
We regularly contribute to large-scale interdisciplinary research projects and develop data processing pipelines and tools for data exploration and visualisation. We are equipped with state-of-the-art computational infrastructure and have access to a comprehensive software repository.
We train the next generation of bioinformaticians through our own research projects, specific courses and our Master program in Bioinformatics and Computational Biology.
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OpenGenomeBrowser is a self-hostable, open-source software that manages access to genomic databases and drastically simplifies basic comparative genomics analysis steps. It allows users to filter genomes based on metadata, create phylogenetic trees, search for annotations, align genes, compare gene loci, interactively browse biochemical pathways, study dotplots, search for orthologous genes, perform gene trait matching, execute BLAST searches, and access the raw data.
We have set up new analysis workflows for spatial transcriptomics and epigenomics.
Check out our services page for more information.
We are in search of a Bioinformatician/Computational Biologist (100%), applications are reviewed on a constant basis (until position is filled).
The BBBHub is a data hub which centralizes and organizes raw and processed RNA-Seq data from reserch in the field of Brain Barriers. This data hub is spearheaded at the Interfaculty Bioinformatics Unit of the University of Bern and is part of the European network BtRAIN.
It is already known that zebrafish can flexibly regenerate their hearts after injury. An international research group led by Prof. Nadia Mercader of the University of Bern now shows that certain heart muscle cells play a central role in this process. The insights gained could be used to initiate a similar repair process in the human heart.
The latest publication of Dr. Rémy Bruggmann can be found on elifesciences.org.
Collegium Generale Lecture Series: Dr. Rémy Bruggmann, head of the IBU and BCPM management board member, speaks about Bioinformatics und new Sequencing Technologies (Podcast in German).
The Interfaculty Research Cooperation "One Health: Cascading and Microbiome-Dependent Effects on Multitrophic Health" examines causal relationships between environmental, animal and human health. We investigate how environmental chemicals such as heavy metals, pesticides and plant secondary metabolites affect microbial communities and health at the interfaces between soils, plants, animals and humans. By unraveling underlying mechanisms, our work contributes to a better understanding of integrated health and supports the development of healthy food chains.
[Text from onehealth.unibe.ch]
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