Signatures of Inversions and Locally Adapted Alleles
Thomas Behrens
With simulations of evolutionary dynamics using the software SLiM, I am investigating patterns of diversity, differentiation, and linkage disequilibrium resulting from chromosomal inversions capturing locally adapted alleles. Ultimately, these results will be compared to molecular signatures in natural data to better understand the establishment of inversions in natural populations.
Immune evasion in pandemic
Sylvie Tillé
I am interested to understand how an immune evasion of a virus can occur in a pandemic where there is vaccination. For this I implement simulation of SIR models, an epidemiological compartmental model. The goal is to understand which factors influence and explain the vaccination evasion of a virus in a network structure population in particular the vaccination strategy and how the behaviour of the population can influence the evolution of the disease.