Differential methylation (DM) analysis

We use data from whole genome or reduced representation bisulfite sequencing to test for differential methylation between experimental groups. Our workflow relies on the nf-core methylseq pipeline to perform the alignment and methylation calling. This is followed by an in-house pipeline which tests for differential methylation at the level of individual CpGs and larger genomic regions.

 

  • Documentation (download below)
  • Quality report and plots

 

Differential methylation analysis

  • Differentially methylated CpGs
  • Differentially methylated genomic regions

 

A zip archive containing the results from an example analysis can be downloaded below. Please refer to the included README and the documentation for more details.